Aminobenzoic acids and derivatives
Apexbio Technology LLC Ac-IETD-pNA 219138-21-3 25mg
Ac-IETD-pNA (CAS 219138-21-3) is a synthetic peptide substrate designed for colorimetric detection of caspase-8 activity as well as related cysteine proteases such as caspase-6 caspase-10 and granzyme B The IETD sequence within Ac-IETD-pNA corresponds to the canonical cleavage site recognized by caspase-8 enabling specific substrate hydrolysis during apoptosis Upon enzymatic cleavage p-nitroaniline (pNA) is released and quantified spectrophotometrically at 405 nm providing a direct measure of protease activity in cell lysates This compound is widely employed for the identification and quantification of caspase-8 activation and facilitates the study of downstream apoptotic signaling pathways in biomedical research
Medchemexpress LLC p-Hydroxymandelic acid | 1198-84-1 | 95.5% | 168.15 | 500 MG
p-Hydroxymandelic acid is a valuable aromatic fine chemical and widely used for production of pharmaceuticals and food additives. It is also used in the production of aromatic drugs and flavors, and for the preparation of 4-hydroxyphenylacetic acid, a synthetic precursor of the selective β1-receptor antagonist drug atenolol. Additionally, p-Hydroxymandelic acid can conjugate cytotoxic drugs and enzyme substrates, suggesting its application in targeted drug delivery systems.
- Valuable aromatic fine chemical.
- Used for production of pharmaceuticals.
- Used for production of food additives.
- Applied in targeted drug delivery systems.
Selleck Chemical LLC Purvalanol A
Purvalanol A is a potent and cell-permeable CDK inhibitor with IC50 of 4 nM 70 nM 35 nM and 850 nM for cdc2-cyclin B cdk2-cyclin A cdk2-cyclin E and cdk4-cyclin D1 respectively Purvalanol A induces endoplasmic reticulum stress-mediated apoptosis and autophagy
ILEX LIFE SCIENCES LLC ACTIVE GHRELIN ELISA 2 X 96W
Yanaihara Institute Active Ghrelin Human/Rat/Mouse ELISA Kit (2 x 96 wells). DESCRIPTION: Active Ghrelin Human/Rat/Mouse ELISA kit, developed and manufactured in Japan by Yanaihara Institute Inc., is used for quantitative measurement of the active form of Ghrelin in plasma samples. This multispecies assay can detect not only octanoylated human Ghrelin but also octanoylated rat/mouse Ghrelin (1-28). The kit uses the highly specific antibody pairs generated by Dr. Kangawa and by following his protocol. QUANTITY: With one 96-well plate, 40 samples can be measured in duplicate. The plate consists of 8-well strips that can be used separately. NOTE: This assay uses the same antibody as the discontinued LSI Medicine Active Ghrelin ELISA (cat. no. 97751). ASSAY RANGE: 2.9 - 184 fmol/mL. OTHER NAMES: Acylated ghrelin (AG), Acyl-ghrelin, octanoyl ghrelin, Appetite-regulating hormone, GH secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, GHRL, MTLRP.
ILEX LIFE SCIENCES LLC SIRCOL ISO-CONC RGT 3 X 20ML
Biocolor Sircol Isolation-Concentration Reagent (3 x 20 ml), component for use with Sircol Soluble Collagen Assay. The Biocolor Sircol Soluble Collagen Assay is a quantitative assay for measurement of both acid-soluble and pepsin-soluble collagens. The colorimetric assay is a dye-binding method using Sircol Dye Reagent, which contains Sirius Red dye in picric acid. This kit is suitable for all soluble mammalian collagens, Types I to V. The assay can assess the rate of newly synthesized collagen. New collagen is produced during periods of rapid growth and development. New collagen is also generated during inflammation, wound healing and tumor development. The Sircol Assay can monitor collagen produced in situ, or during in-vitro cell culture. It can also measure in-vitro extracellular matrix (ECM) formation.